With the beginning of the Renaissance in the 17th century, a new way of thinking was initiated in the world of philosophy and science. Although the holistic approach was a popular way of thinking among philosophers in ancient Greece, it cannot be said that there was an important theoretical recovery in these periods. This movement in Europe is primarily Rene Descartes, who wrote books on scientific methods and brought important rules. This groundbreaking philosopher was followed by the great physicist Isaac NEWTON. On the other hand, in Germany, Leibniz has taken important steps on theoreticality and holism with an approach similar to Descartes. In the 20th century, with the great journey Charles Darwin made with his holistic point of view, holisticization also took an important step. At the beginning of the 20th century, Albert EINSTEIN fundamentally established the Darwin's-like important point of view in physics and astrophysics in his perspective on the universe and atoms. This book, in my opinion, was an important step calling for holistic thought, which became increasingly impoverished at the beginning of the 20th century.