There is a mystery that lies buried deep beneath the sands of Egypt, an ancient structure consumed by the desert thousands of years ago. It is a legend that Professor Fathom's men?treasure-hunter Jake Stone, Brazilian biologist Eden Santiago, Texas cowboy Shane Houston, Italian art expert Luca da Roma, and quarterback Will Hunter?must find in order to save one of their own.

But within every shadow lies a secret, around every corner hides danger... and time is running out. Will they be able to solve the mystery, survive the traps and uncover the perilous Pyramid of Puzzles before it's too late? Or will the sand finally slip through the hourglass for Fathom's Five?